Hepatic adenomas and oral contraceptives

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Hepatic adenomas and oral contraceptives.

Over the past 5 years there has been an increase in the number of reports of patients with hepatic adenomas, and an association has been found between these tumors and the use of oral contraceptives. Up to January 1975 46 patients have been reported with this association. The histology of the tumors varies, with several names having been applied to the variations. Adenoma or focal nodular hy...

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Hepatocellular Adenomas Associated with Hepatic Granulomas: Experience in Five Cases

We present five cases in whom two rare entities were simultaneously found within the liver, i.e. hepatocellular adenomas (HCAs) and granulomas. Coexistence of both entities confuses diagnosis. Our aim is to disclose the association between HCA and hepatic granulomas. Five patients presented with HCA for which they underwent resection. During laparotomy or at pathological examination, granulomas...

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Liver resection for hepatic adenoma.

Between 1970 and 1978, eight hepatic adenomas were resected. Four of the eight patients took oral contraceptive pills before the hepatic adenoma was identified; one patient was male. Four patients had evidence of bleeding at the time of presentation. The original histologic diagnosis in the first five patients was malignant hepatoma. There has been no known recurrence of tumor and all patients ...

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Life-Threatening Complications of Hormonal Contraceptives: A Case History

We present a case with the rare combination of thrombotic and hemorrhagic complications of oral contraceptives. A healthy 40-year-old woman suffered from cardiac arrest due to massive pulmonary embolism, caused by oral contraceptives and immobilization during a flight. After successful resuscitation, obstructive shock necessitated thrombolysis and thereafter heparin. Anticoagulation was complic...

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Regarding 'Liver cell adenoma and liver cell adenomatosis' by Ludger Barthelmes and Iain S. Tait.

We read with great interest the recent article by Barthelmes and Tait (HPB 2005;7:186 /196). The impact of the diagnosis ‘liver cell adenoma’ on the life of a young female patient is enormous. Conservative management of liver cell adenoma frequently implies cessation of oral contraceptives, regular follow-up including radiological imaging, and negative advice regarding pregnancy. Surgical treat...

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تاریخ انتشار 2006